Clonidine
In brief
- In our pharmacy, you can buy clonidine without a prescription, with delivery available throughout the United Kingdom. Discreet and anonymous packaging.
- Clonidine is used for the treatment of hypertension. It works as an antihypertensive by stimulating alpha-2 adrenergic receptors in the brain, decreasing sympathetic outflow and thereby reducing blood pressure.
- The usual starting dose of clonidine for hypertension is 50–100 micrograms taken three times daily, increased gradually as needed.
- The form of administration is oral tablets.
- The effect of the tablets begins within 30 to 60 minutes.
- The duration of action of the tablets typically lasts about 6 to 12 hours.
- Alcohol should be avoided as it may increase the risk of CNS depression and hypotension when combined with clonidine.
- The most common side effect is dry mouth.
- Would you like to try clonidine without a prescription?
Basic clonidine information
- INN (international nonproprietary name): Clonidine
- Brand names available in the United Kingdom: Catapres; generic clonidine
- ATC code: C02AC01
- Forms and dosages: Tablets 25 micrograms and 100 micrograms; solution for injection (hospital use)
- Manufacturers in the United Kingdom: Generic manufacturers
- Registration status in the United Kingdom: Prescription-only medicine (POM)
- OTC / Rx classification: Prescription-only medicine (POM)
Everyday use and best practices
Clonidine tablets are usually taken two or three times a day. The timing should follow the advice of your healthcare provider.
Morning vs evening dosing
Clonidine can be taken in the morning or evening, guided by your healthcare provider's advice. Because it can cause drowsiness, the larger part of the daily dose is sometimes taken in the evening. Take doses at regular times each day, and do not stop taking it suddenly, as this can cause a rebound rise in blood pressure.
Taking with or without meals
Clonidine can be taken with or without food. Taking it with a meal may help if it upsets your stomach. Keeping the doses at regular times in relation to meals helps to maintain steady levels of the medicine.
What’s inside and how it works
Ingredients overview
The primary active ingredient in clonidine is clonidine hydrochloride, available as 25 microgram and 100 microgram tablets. Inactive ingredients may vary by formulation and usually include fillers and stabilisers to ensure stability and efficacy.
Mechanism basics explained simply
Clonidine functions as an alpha-2 adrenergic agonist, a mechanism that reduces the release of noradrenaline from sympathetic nerves. This contributes to a reduction in heart rate and blood pressure by relaxing blood vessels.
Main indications
Approved uses
Clonidine is licensed in the UK for the treatment of hypertension (high blood pressure), where it works by decreasing heart rate and relaxing blood vessels. It has also been licensed for the prevention of migraine and for menopausal flushing.
Off-label uses in UK clinics
Clonidine is also prescribed off-label by specialists, for example in ADHD, to ease opioid withdrawal symptoms, and for anxiety and sleep disturbances. These uses are not part of the licence, so the prescriber should discuss the potential risks and benefits with the patient first.
Delivery information
| City | Region | Delivery Time |
|---|---|---|
| London | Greater London | 9–21 days |
| Birmingham | West Midlands | 9–21 days |
| Manchester | North West | 9–21 days |
| Glasgow | Scotland | 9–21 days |
| Leeds | West Yorkshire | 9–21 days |
| Sheffield | South Yorkshire | 9–21 days |
| Bristol | South West | 9–21 days |
| Newcastle | Tyne and Wear | 9–21 days |
| Coventry | West Midlands | 9–21 days |
| Cardiff | Wales | 9–21 days |
| Nottingham | East Midlands | 9–21 days |
| Southampton | South East | 9–21 days |
| Portsmouth | South East | 9–21 days |
