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Cilodex

Cilodex
In stock
0.3/0.1%
from 27,73 £
Strength
Pack size — the bigger the pack, the cheaper the tablet
33,27 £ 27,73 £
27,73 £ per bottle

In brief

  • Cilodex is a prescription-only medicine (POM) in the UK.
  • Cilodex is used for the treatment of acute otitis media and acute otitis externa. It combines ciprofloxacin, an antibiotic, with dexamethasone, a corticosteroid, to provide antibacterial coverage and reduce inflammation.
  • The usual dosage of cilodex is 4 drops in the affected ear(s) twice daily for 7 days.
  • The form of administration is an ear drop suspension.
  • Symptoms usually start to improve within the first few days of treatment.
  • The most common side effect is ear discomfort.
  • Would you like to try cilodex without a prescription?

Basic Cilodex information

International nonproprietary name (INN) Ciprofloxacin and dexamethasone
Brand names available in the United Kingdom Cilodex
ATC code S02CA06
Forms and dosages Ear drops, suspension (ciprofloxacin 0.3% / dexamethasone 0.1%)
Manufacturers in the United Kingdom Alcon
Registration status in the United Kingdom Prescription-only medicine (POM)
OTC / Rx classification Prescription-only medicine (POM)

Everyday use and best practices

Morning vs evening dosing

Maintaining a consistent routine is essential when using Cilodex. It should be used at the same times each day, usually in the morning and evening about 12 hours apart, to ensure maximum effectiveness. Strategies to help remember your doses:
  • Set an alarm on your phone.
  • Establish a routine, such as using the drops after brushing your teeth.
Consistency aids effective treatment.

Taking with or without meals

Cilodex is applied to the ear and not swallowed, so meals make no difference. Practical tips:
  • Warm the bottle in your hand for a minute or two before use, and shake it well.
  • Lie with the affected ear upwards and stay in that position for about a minute after the drops are in.
  • If you miss a dose, use it when you remember unless it is nearly time for the next one; do not double up.

Safety priorities

Who should avoid it

Certain conditions may prevent the use of Cilodex. Individuals who should not use Cilodex:
  • Those with known hypersensitivity to ciprofloxacin, dexamethasone, or other ingredients in the formulation.
  • Patients experiencing viral, fungal, or mycobacterial infections in the ear.
  • Anyone with a history of significant allergic reactions to fluoroquinolones or corticosteroids.

Activities to limit

Cilodex is applied to the ear and is not expected to affect driving or the use of machinery. If you feel dizzy after using the drops, wait until it passes before driving.

Dosage and adjustments

General regimen

Following the standard dosing guidelines is crucial for effective treatment. The recommended regimen for adults and children is:
  • Acute otitis media in children with tympanostomy tubes: 4 drops in the affected ear(s) twice daily for 7 days.
  • Acute otitis externa (swimmer’s ear): 4 drops in the affected ear(s) twice daily for 7 days.

Special cases

Certain patient groups may require special attention while using Cilodex.
  • Elderly patients: No dosage adjustment is typically required, but they should be monitored for any adverse reactions.
  • Those with comorbidities: Careful evaluation is vital, especially if they have existing ear infections or allergies.
A healthcare provider can advise on any individual precautions.

What’s inside and how it works

Ingredients overview

Cilodex combines two active ingredients: Ciprofloxacin and Dexamethasone. Ciprofloxacin is a fluoroquinolone antibiotic, which works by inhibiting the bacteria's ability to replicate, and is active against common ear pathogens such as Pseudomonas aeruginosa. Dexamethasone is a corticosteroid that reduces inflammation, pain and swelling. This combination treats the infection while also soothing the affected area.

Mechanism basics explained simply

Cilodex functions by tackling ear infections mainly found in acute otitis media and acute otitis externa. When administered, the ciprofloxacin combats the underlying bacterial infection, while the dexamethasone lessens inflammation, which helps relieve discomfort.

Main indications

Approved uses

Cilodex is licensed in the UK for specific conditions affecting the ear. It is indicated for:
  • Acute otitis media (AOM) in children with tympanostomy tubes.
  • Acute otitis externa (swimmer’s ear) in patients aged six months and older.

Off-label uses in UK clinics

In addition to its licensed uses, clinicians may sometimes prescribe Cilodex off-label, for example for post-surgical ear infections, based on clinical judgement.

Interaction warnings

Food interactions

Because Cilodex is used in the ear, food and drink have little effect on this medication.

Drug conflicts

Very little of the medicine is absorbed from the ear, so interactions are unlikely. Patients should tell healthcare providers about other ear drops and medicines they are using. Suspected side effects can be reported through the Yellow Card scheme.

Alternative choices

When considering alternatives to Cilodex (ciprofloxacin and dexamethasone ear drops), it is essential to weigh various options. Each has unique pros and cons.
  • Otovel: Combines ciprofloxacin with fluocinolone acetonide. Used for similar conditions, but side effects may vary.
  • Ofloxacin ear drops: Contain only ofloxacin. While effective against bacterial infections, they lack the anti-inflammatory benefits of the corticosteroid in Cilodex.
  • Neomycin, polymyxin B and hydrocortisone ear drops: This option has a steroid and a broader antibacterial spectrum, though the allergy risk is higher.
Each of these alternatives has its merits and drawbacks. Cilodex combines antibacterial action and inflammation reduction. A healthcare provider can advise on the right choice based on personal health needs.

Regulation snapshot

Cilodex is regulated by the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK.
Cilodex is a prescription-only medicine (POM), which reflects the necessity for professional oversight during use.

Frequently asked questions

Common questions arise regarding Cilodex, particularly from patients dealing with ear infections. Here are a few typical concerns:
  • What is Cilodex used for?
    Cilodex is formulated to treat bacterial ear infections, particularly acute otitis media and acute otitis externa.
  • Can Cilodex be used with ear tubes?
    Yes, Cilodex can be prescribed for patients with tympanostomy tubes. Always consult a healthcare provider for specific advice.
  • Are there side effects?
    Some patients experience minor issues like ear discomfort or itching. Serious side effects are rare but should be discussed with a doctor if they arise.
  • Is Cilodex available over the counter?
    No. In the UK, Cilodex is a prescription-only medicine.

Guidelines for proper use

To maximise the effectiveness of Cilodex, adherence to the prescription is crucial. Here are some key guidelines:
  • Administer 4 drops into the affected ear(s) twice a day for up to 7 days, or as directed.
  • Make sure to shake the bottle well before use.
  • Avoid touching the dropper to any surfaces to maintain sterility.
  • If a dose is missed, administer as soon as possible unless it is near the next scheduled dose. Do not double up.
Pharmacists can play an essential role in ensuring patients understand how to use their ear drops correctly. They should provide counselling that includes:
  • Monitoring for any potential side effects or allergic reactions.
  • Reminders not to exceed the prescribed dosage, even if symptoms seem to improve.
NHS patient information is available for ongoing support.
City Region Delivery Time
London Greater London 9–21 days
Birmingham West Midlands 9–21 days
Manchester Greater Manchester 9–21 days
Glasgow Scotland 9–21 days
Bristol South West 9–21 days
Leeds West Yorkshire 9–21 days
Sheffield South Yorkshire 9–21 days
Edinburgh Scotland 9–21 days
Cardiff Wales 9–21 days
Newcastle Tyne and Wear 9–21 days
Nottingham East Midlands 9–21 days
Coventry West Midlands 9–21 days
Leicester East Midlands 9–21 days
Brighton South East 9–21 days
Swindon South West 9–21 days

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