Brand Viagra

Basic Brand Viagra information

• INN (international nonproprietary name): Sildenafil
• Brand names available in the United Kingdom: Viagra, Viagra Connect; generic sildenafil
• ATC code: G04BE03
• Forms and dosages: Film-coated tablets 25 mg, 50 mg, 100 mg
• Manufacturers in the United Kingdom: Pfizer/Upjohn (Viagra); generics from Accord, Teva and others
• Registration status in the United Kingdom: Viagra is a prescription-only medicine (POM); Viagra Connect 50 mg is a pharmacy (P) medicine
• OTC / Rx classification: Prescription-only medicine (POM); Viagra Connect 50 mg: pharmacy (P) medicine

Everyday use and best practices

Viagra is taken as needed, about one hour before sexual activity, and no more than once a day. The time of day does not matter; choose a dose time that fits the planned activity.

Taking with or without meals

Viagra can be taken with or without food, but taking it on an empty stomach gives a faster onset, while a heavy or fatty meal can delay its effect. Bear this in mind when planning:

• Avoid heavy or fatty foods if planning to take the drug, as these can slow its absorption.
• Moderate consumption of alcohol should also be noted; while a drink or two may not hinder effectiveness, excessive drinking can lead to complications.

What’s inside and how it works

The active ingredient in Viagra is sildenafil (as sildenafil citrate).

As for inactive ingredients, they can include substances such as microcrystalline cellulose and magnesium stearate, among others. Those who have known sensitivities should check the ingredient list in the patient information leaflet.

Ingredients overview

Sildenafil is the active ingredient in Viagra and is used for erectile dysfunction. Check the list of inactive ingredients if you are prone to allergies, and consult a healthcare professional if you are unsure.

Mechanism basics explained simply

Sildenafil works by enhancing blood flow to the penis, which is crucial for achieving and maintaining an erection. It achieves this by inhibiting an enzyme called phosphodiesterase type 5 (PDE5), allowing relaxation of blood vessels and enabling increased blood flow when coupled with sexual stimulation.

Main indications

Viagra is used to treat erectile dysfunction and is licensed for this by the Medicines and Healthcare products Regulatory Agency (MHRA) in the UK.

Approved uses (MHRA listing)

The main approved indication for Viagra is erectile dysfunction. This means it’s specifically prescribed for men who struggle to achieve or maintain an erection adequate for sexual activity. It's crucial to use it under medical supervision to tailor treatment to individual health needs effectively.

Off-label uses in UK clinics

Sildenafil is also used for pulmonary arterial hypertension, but under a different product licence (Revatio) and at different doses. Any use of Viagra outside its licensed indication requires proper consultation with a healthcare professional.

Interaction warnings

Certain foods, drinks and medicines can affect how well Viagra works or its safety.

Food interactions (alcohol, tea/coffee)

Alcohol can interfere with erections and add to side effects such as dizziness. Caffeine from tea or coffee doesn't have a significant impact.

Drug conflicts

Viagra can interact with various medications, leading to unintended side effects. Viagra must not be taken with nitrates (including nitrate-containing medicines such as GTN), and caution is needed with alpha-blockers and other blood pressure medicines, which may heighten the risk of low blood pressure. Suspected side effects can be reported through the Yellow Card scheme.

Alternative choices

Other options for erectile dysfunction include:

NHS prescribing alternatives

• Tadalafil:
  • Pros: Longer duration (up to 36 hours); a low daily dose is also available.
  • Cons: Side effects such as back pain and muscle aches.
• Vardenafil:
  • Pros: Similar efficacy to sildenafil.
  • Cons: Similar side effects, including headache and flushing.
• Avanafil (Spedra):
  • Pros: Quick onset of action.
  • Cons: Fewer long-term data.

Always consult a healthcare provider for personalised recommendations.

Regulation snapshot

In the UK, Viagra is licensed by the Medicines and Healthcare products Regulatory Agency (MHRA). Viagra tablets (25 mg, 50 mg and 100 mg) are prescription-only medicines (POM).

Viagra Connect (sildenafil 50 mg) is classified as a pharmacy (P) medicine: it is sold only by a pharmacist, after a consultation, and is not available from general shops.

Pharmacists play a crucial role in advising on the appropriate use of Viagra, including dose and potential side effects. Patients are encouraged to consult healthcare professionals for personalised advice.

Frequently asked questions

Common questions about Viagra:

• Can I take Viagra with other medications? It’s essential to consult a healthcare provider before combining Viagra with other medications, particularly nitrates, as this can lead to serious complications.
• What should I do if I experience side effects? If side effects occur, such as headaches or dizziness, it’s recommended to discuss these with a pharmacist or doctor. They may provide alternatives or suggestions for managing these effects.
• How long does Viagra take to work? Typically, Viagra starts to work about 30 minutes to 1 hour after consumption, but this can vary based on individual circumstances.
• Is Viagra safe for everyone? While Viagra is effective for many men with ED, it’s not suitable for everyone. Those with certain health conditions should use it under strict medical guidance.

Guidelines for proper use

UK pharmacist counselling style

Here are some practical tips for a consultation with a pharmacist about Viagra:

• Discuss your medical history, including any heart conditions or medications you are currently taking.
• Ask about possible side effects and what to watch out for after taking Viagra.
• Inquire about the best dosage for your needs and whether any adjustments are necessary.
• Explore any alternative treatments if Viagra is not the right fit for you.

NHS patient support advice

Essential tips for patients treated with Viagra:

• Follow the prescribed dosage to avoid potential health risks associated with overuse.
• Familiarise yourself with common side effects and seek medical attention if severe reactions occur.
• Use NHS resources, such as the NHS website, for ongoing support and information.
• Consider lifestyle changes, such as diet and exercise, that can enhance overall sexual health.